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Exploring Skin Metabolites Using Non-Invasive Sampling

You are warmly invited to attend the BRCB Friday afternoon seminar.

Speaker: Skaidre Jankovskaja, Tokyo University of Agriculture and Technology

Talk overview

Skaidre Jankovskaja received her PhD in Biomedical Sciences from Malmö University in 2021. During her PhD, she worked on targeted LC-MS-based metabolite analysis, focusing on tryptophan metabolism via the kynurenine pathway. This included investigating changes in the tryptophan-kynurenine ratio in skin cancer models, studying metabolite diffusion across the skin, and optimizing non-invasive skin surface metabolite sampling.

As a postdoctoral researcher at Malmö University, she investigated polar metabolites collected from the skin surface of melanoma patients using non-invasive sampling. This work revealed higher levels of polar metabolites and reduced skin resistance in melanoma lesions compared to non-lesional skin, indicating a compromised skin barrier. These findings suggested that the skin lipidome may be altered in melanoma.

In her current postdoctoral fellowship at Tokyo University of Agriculture and Technology, her research focuses on lipidomics profiling of tape-stripped skin samples from healthy volunteers and melanoma patients. In this seminar, Skaidre will present an overview of her work at Malmö University and preliminary lipidomics results from healthy human volunteer skin.

We look forward to seeing you there!