Enzymatic activity in oral biofilms – biotechnological applications and putative predictive biomarkers for oral disease

While several studies have advanced our knowledge regarding the microbial composition in the oral flora in health and disease, the underlying role of enzymes and their regulation has mainly been disregarded. Herein, I will investigate the impact of glycosidase expression in oral flora during health/disease. My studies are expected to lead to the identification of novel biomarkers for oral health and disease, an area in need of novel, rapid and robust methods for diagnosis and novel biotechnological tools as analytical reagents for biopharmaceuticals.