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On the page
Presentation
I am a Senior lecturer in Oral Microbiology and Associate Professor in experimental infection medicine.
My research is focused on elucidation of host-bacteria interactions during the transition from carriage to opportunistic infection or invasive disease. We aim to understand the interplay and adaptation of bacteria within oral biofilms and how these bacteria modulate the function of critical players in the innate immune defences during oral or systemic disease. We develop and apply ex-vivo and in-vivo models of infection, with the aim to identify critical interfaces that can be targeted for development of biomarkers or immunomodulatory therapeutic interventions.
I am an active university teacher and examiner within the subjects of microbiology and immunology.
Publications
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2024 | Article in journal
Biofilm-dispersed pneumococci induce elevated leukocyte and platelet activation
Yashuan Chao, Martina Mørch, Anders P. Hakansson, Oonagh Shannon
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2024 | Article in journal
Quantification of Adaptive Immune Responses Against Protein-Binding Interfaces in the Streptococcal M1 Protein
Eva Torres-Sangiao, Lotta Happonen, Morizt Heusel, Frida Palm, Carlos Gueto-Tettay, Lars Malmström, Onna Shannon, Johan Malmström
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2024 | Article in journal
A novel multiplex fluorescent-labeling method for the visualization of mixed-species biofilms in vitro
Olivia Aherne, Martina Mørch, Roberto Ortiz, Oonagh Shannon, Julia R Davies
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2024 | Article in journal
The hinge-engineered IgG1-IgG3 hybrid subclass IgGh 47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies
Arman Izadi, Yasaman Karami, Eleni Bratanis, Sebastian Wrighton, Hamed Khakzad, Maria Nyblom, Berit Olofsson, Lotta Happonen, Di Tang, Martin Sundwall, Magdalena Godzwon, Yashuan Chao, Alejandro Gomez Toledo, Tobias Schmidt, Mats Ohlin, Michael Nilges, Johan Malmstrom, Wael Bahnan, Oonagh Shannon, Lars Malmstrom, Pontus Nordenfelt
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2023 | Article in journal
Phenotypic characterization of acoustically enriched extracellular vesicles from pathogen-activated platelets
Frida Palm, Axel Broman, Genevieve Marcoux, John W. Semple, Thomas L. Laurell, Johan Malmström, Oonagh Shannon
